Soru

A $31$-year-old woman, gravida 2, para 1, at $9$ weeks gestation presents to the emergency department with a $2$-day history of severe agitation, palpitations, vomiting, and diarrhea. She has a history of Graves disease, for which she stopped taking her medications when she discovered she was pregnant. She also has a history of severe persistent asthma requiring daily fluticasone and salmeterol inhalers, with her last exacerbation requiring endotracheal intubation three years ago.

On physical examination, her temperature is $39.4^\circ\text{C}$ ($102.9^\circ\text{F}$), blood pressure is $152/68\text{ mmHg}$, heart rate is $158/\text{min}$ and regular, and respiratory rate is $26/\text{min}$. She is delirious, markedly tremulous, and diaphoretic. A diffusely enlarged, non-tender thyroid gland is palpable. Lung auscultation reveals diffuse bilateral end-expiratory wheezing.

Laboratory testing shows:
Thyroid-stimulating hormone (TSH): $<0.01\text{ \mu U/mL}$
Free thyroxine (T4): $5.4\text{ ng/dL}$ (Reference: $0.8-1.8\text{ ng/dL}$)

An electrocardiogram shows sinus tachycardia.

Which of the following are appropriate initial pharmacologic interventions for this patient? (Select all that apply)