A 24-year-old woman is brought to the emergency department by ambulance due to severe shortness of breath, wheezing, and a tight chest that began 2 hours ago. She has a history of moderate persistent asthma but has not used her inhalers for the past week. On arrival, she appears anxious and is using accessory muscles of respiration. Her temperature is (), blood pressure is , pulse is , and respiratory rate is . Oxygen saturation is on room air. Physical examination reveals diffuse bilateral end-expiratory and inspiratory wheezes. Laboratory studies show a leukocyte count of with a normal differential. Which of the following pharmacologic interventions should be administered as part of her immediate initial management? (Select all that apply)
- Nebulized albuterol and ipratropiumCevap
- Intravenous methylprednisoloneCevap
- CIntravenous propranolol
- DInhaled fluticasone
- EIntravenous ceftriaxone