A 55-year-old woman is preparing for discharge following an admission for a non-ST-segment elevation myocardial infarction (NSTEMI). She underwent a successful percutaneous coronary intervention with the placement of a drug-eluting stent. Her past medical history includes hypertension and hyperlipidemia. Her vitals are temperature (), blood pressure , pulse , and respiratory rate . An echocardiogram demonstrates a left ventricular ejection fraction of . In addition to dual antiplatelet therapy with aspirin and clopidogrel, which of the following pharmacologic interventions should be included in her discharge regimen to provide a long-term mortality benefit? (Select all that apply)
- AtorvastatinCevap
- MetoprololCevap
- CIbuprofen
- DFlecainide
- ERivaroxaban
Cevap
The correct interventions are Atorvastatin and Metoprolol.
Both high-intensity statins (like atorvastatin) and beta-blockers (like metoprolol) are foundational secondary prevention therapies following an acute coronary syndrome. Statins stabilize atherosclerotic plaques and reduce the risk of recurrent cardiovascular events, while beta-blockers decrease myocardial oxygen demand, inhibit adverse cardiac remodeling, and reduce the risk of fatal arrhythmias, collectively conferring a significant mortality benefit.
Adım Adım Çözüm
Anahtar Kavram
Secondary pharmacologic prevention following an acute coronary syndrome requires a beta-blocker, a high-intensity statin, and dual antiplatelet therapy to optimize long-term mortality outcomes.
Tahmini Süre:45s