Soru

A $78$-year-old woman is evaluated in the outpatient clinic for a $3$-week history of increased confusion and two recent falls. She lives alone, and her daughter reports that the patient has been forgetting recent conversations and appearing unusually unsteady on her feet. Her past medical history includes hypertension, type 2 diabetes mellitus, overactive bladder, and insomnia. Her current daily medications are metformin, lisinopril, amlodipine, oxybutynin, and amitriptyline. Her blood pressure is $135/80$ mm Hg lying down and $110/65$ mm Hg standing. Her pulse is $82$/min lying down and $96$/min standing. Physical examination is notable for a dry oral mucosa and delayed cognitive recall. Laboratory results, including a comprehensive metabolic panel and urinalysis, are within normal limits. Which of the following are appropriate pharmacologic interventions for this patient? (Select all that apply)